PRACTICAL LESSONS: 1. Introduction. Protection against external and internal radiation. Workplaces with radioactive substances Assigments of topics of seminar works. 2. Methods of radioactivity control. 3. Methods of detection of radiation effect on the embryonic development. 4. Changes in carbohydrate metabolism after radiation. 5. Genetic consequences of radiation – Mutations. 6. Changes in enzymes after radiation. 7. Radiation effects on cellular level. 8. Heritable genetics effect of radiation. 9. Changes in lipid metabolism after radiation. 10. Late effects of IR: radiation carcinogenesis. 11. Credit test. 12. Macroscopic changes and post-radiation changes in peripheral blood. 13. Handover of seminar works. LECTURES: 1.Introduction: Radiation and life. Short history of radiation biology. 2. Basic physics of ionozing radiation. Kinds of ionizing radiation. Units of radioactivity and ionizing radiation. 3. Effect of radiation on the embryonic development. 4. Effects of IR on nuclear acids and proteins. 5. Genetic consequences of radiation – Mutations. 6. Mechanism of the action of IR on living systems. Direct and indirect effect of IR. Dose distribution in living organism. 7. Radiation effects cellular level. 8. Heritable genetics effect of radiation. 9. Pathophysiology of ionizing radiation. Radiation syndromes. 10. Late effects of IR: radiation carcinogenesis. 11. Health effects of the most important radionuclides. Ways of input of radionuclides into human body and their fate in the body. Mechanism of the excretion of radionuclides. 12. Radiation and immunity. 13. Radiation and nuclear science. |