LECTURES 1.Introduction to clinical genetics. 2.Basic of cytogenetics chromosomes and karyotypes of domestic animals. 3.Overview of chromosome aberrations and their relationship to animal health 4.Hereditary developmental disorders of livestock. Genes with lethal effect. 5.Genetics of animal coat colour in relation to hereditary diseases. 6.Genetics of fertility disorders. 7.Mutagenesis, teratogenesis and carcinogenesis. Genetics and cancer. 8. Overview of multifactorial diseases. 9. Health heritage control. 10. Gene therapy. 11. Animal genome analysis GWAS 12. Cloning of animals and preparation of transgenic livestock in relation to their health status. 13. Ethical aspects of clinical genetics and modern biotechnology. PRACTICALS 1.Genetic counselling the use of pedigrees in the study of the transmission of hereditary diseases in families. 2.Practical preparation of slides for cytogenetic analysis. 3.Microscopic observation of metaphases of livestock and companion animals. Comparison of the number and morphology of chromosomes. 4.Developmental disorders of companion animals. 5.Genetics of coat color. 6. Sexual development disorders - cases from clinical practice. 7. Mutagenicity tests. 8.Neurogenetics. Behavioral genetics. Genetic and different types of addictions. 9. DNA diagnostics of hereditary diseases. 10.Gene therapy in veterinary practice. 11. Editing the human and animal genomes. Descendants of three parents. 12. Health and ethical aspects of cloning and construction of transgenic animals. 13. Economic and legal issues of modern biotechnology. Credit test. |