In order to pass the course, the student must have active participation in lectures and practical training. The prerequisite for passing the examination is the preparation and defence of a seminar paper on the topic assigned by the supervisor (in the range A-E), which is the result of self-study. The examination is awarded on the basis of an assessment of the knowledge acquired (in the A-E range).

By completing the course, the student acquires up-to-date knowledge of molecular biology, which is applied in clinical molecular genetic diagnostics of hereditary diseases of farm and companion animals. The student acquires the latest knowledge in the field of gene therapy, genetically modified organisms, transgenic animals and modern biotechnology.

Molecular basis of heredity / Function of nucleic acids. The function of nucleic acids in the cell / Transcription and translation in eukaryotes. Chromosomes: ultrastructure and function / Cytogenetics. Chromosome aberrations / Modern methods and significance of cytogenetic analysis in clinical practice. DNA replication / Diseases associated with DNA replication disorders. Gene and its function / Gene mutations. Recombinant DNA methods / Application of recDNA methods. Animal cloning and transgenesis/ Biotechnology and nanobiotechnology. Principles of gene therapy / Current possibilities of gene therapy in companion animals. Epigenetics / Epigenetic diseases. Monogenic and multifactorial inheritance of traits / Prevention of the spread of inherited diseases in farm and companion animals. Animal genome editing / Advances in animal biotechnology. Principles of DNA diagnosis of inherited diseases / Molecular methods used in clinical genetics and DNA diagnosis of inherited diseases.

Molecular basis of heredity / Function of nucleic acids. The function of nucleic acids in the cell / Transcription and translation in eukaryotes. Chromosomes: ultrastructure and function / Cytogenetics. Chromosome aberrations / Modern methods and significance of cytogenetic analysis in clinical practice. DNA replication / Diseases associated with DNA replication disorders. Gene and its function / Gene mutations. Recombinant DNA methods / Application of recDNA methods. Animal cloning and transgenesis/ Biotechnology and nanobiotechnology. Principles of gene therapy / Current possibilities of gene therapy in companion animals. Epigenetics / Epigenetic diseases. Monogenic and multifactorial inheritance of traits / Prevention of the spread of inherited diseases in farm and companion animals. Animal genome editing / Advances in animal biotechnology. Principles of DNA diagnosis of inherited diseases / Molecular methods used in clinical genetics and DNA diagnosis of inherited diseases.

Lodish, H. et al: Molecular Cell Biology, Macmillan, 2013

Mondal, S., Singh, R.L.: Advances in Animal Genomics, Elsevier, 2021

Jalali, M. et al.: Basic Science Methods for Clinical Researchers, Elsevier, 2017

Continuous assessment:

Active participation in lectures and practical training.

Conditions for completion of course:

In order to pass the course, the student must have active participation in lectures and practical training. The prerequisite for passing the examination is the preparation and defence of a seminar paper on the topic assigned by the supervisor (in the range A-E), which is the result of self-study. The examination is awarded on the basis of an assessment of the knowledge acquired (in the A-E range).

Final assessment:

The prerequisite for passing the examination is the preparation and defence of a seminar paper on the topic assigned by the supervisor (in the range A-E), which is the result of self-study.