Lectures 1. Introduction to pharmacology: the historical development, the role, subdivisions of pharmacology and related sciences. 2. Pharmacological nomenclature, designation of drugs, drug names and common dosage forms. An assortment of veterinary pharmaceuticals; the mode of drug use. 3. Dosage regimen, drug doses. 4. Dose-response relationship, drug safety. Administration of drugs; 5. The fate of drug in the body. Pharmaceutical phase. 6. Pharmacokinetics: drug absorption. 7. Pharmacokinetics: drug distribution. 8. Pharmacokinetics: drug biotransformation. 9. Pharmacokinetics: drug excretion. 10. Pharmacodynamics: mechanism of drug action and the effect. Specific pharmacological receptors; drug-receptor interactions. 11. Pharmacodynamics: structure-activity relationship. Potency, selectivity and specificity of drug. Receptor regulation and drug tolerance. Adverse effect of drugs. 12. Special pharmacology: drugs used to treat infectious diseases – antibacterials and parasiticides. 13. Special pharmacology: drugs used to treat various organ systems. Practical exercises 1. Weight units used in pharmacology; calculation of drug doses and dilutions of liquid drugs. 2. Calculation of drug doses based on animal’s body weight and body surface area. 3. Calculation of drug doses of individually and mass administered preparations. 4. Household measures used in veterinary medicene. 5. Prescription: general information, the importance, the structure, the types of prescriptions and the main principles of drug prescribing. 6. Development of Pharmacopeia, European Pharmacopoeia. Veterinary Data Sheet Compendia. 7. Dosage forms, assortment of veterinary pharmaceutical preparations. 8. Mass produced preparations: analysis of MPP against bacterial infections. 9. Mass produced preparations: analysis of MPP against parasitic infections. 10. Mass produced preparations: analysis of MPP used on various organ systems. 11. Symptomatology – pharmacological effects of selected compounds on animals – video projecting. 12. Herbal medicines used in veterinary practice. 13. Credit test, awarding of credits. |